Specialty Areas:

• Image Guided Radiation Therapy Program

Patients Seen At:

• Siteman Cancer Center
  Center for Advanced Medicine
  4921 Parkview Place, Floor LL
  St. Louis, MO 63110
  (314) 747-7236

Mailing Address:

• Washington University School of Medicine
  Department of Radiation Oncology
  4921 Parkview Place, Campus Box 8224
  St. Louis, MO 63110
  (314) 747-3721
  eklein@radonc.wustl.edu

Areas of Clinical Interest:

• Dr. Klein is currently Chief of Physics, Education, in the Physics Division, Department of Radiation Oncology. He is also the director of the Radiation Oncology Physics Residency Program. Dr. Klein is in process to implement a Modulated Electron Radiotherapy program involving Monte Carlo Calculations.

Board Certification:

• Certified, American Board of Radiology in Radiological Physics

Education:

• 1980, Bridgewater State College, Bachelor of Science Degree in Physics
• 1987, Master of Science in Applied Physics
• 2006, Ph.D., Medical Physics, Chicago Medical School/Rosalind Franklin University

Selected Publications:

• Klein, E.E, Gerber, R., Zhu, X.R., Oehmke,F., Purdy, J.A. Multiple Machine Implementation Of Enhanced Dynamic Wedge, Int. J. Rad. Onc. Biol. Phys., 1998; 40, 977-985.
• Zhu, X.R., Klein, E.E., Low, D.A., Geometric and Dosimetric Analysis of Multileaf Collimation Conformity, Radiotherapy and Oncology, 1998; 47, 63-68.
• Klein, E.E., Modulated Electron Beams Using Multi-segmented Multileaf Collimation Radiotherapy and Oncology, 1998; 48, 307-311.
• Klein E.E., Drzymala R.E., Williams R. Westfall L.A., Purdy J.A., A Change In Treatment Process With A Modern Record And Verify System, IJORBP, 1998; 42, 1163-1168.
• Klein, E.E., Tepper, J., Sontag, M., Franklin, M., Ling, C., Kubo, D. Technology Assessment of Multileaf Collimation: A North American Users Survey, IJORBP, 1999; 33, 705-710.
• Mutic, S, Klein, E.E. A Reduction in the AAPM TG-36 Reported Peripheral Dose Distributions with Tertiary Multileaf Collimation, IJORBP; 44, 947-953, 2000.
• Klein, EE, Low DA, Sohn JW, Purdy JA. Feasability Of Differential Dosing Of Prostate And Seminal Vesicles Using Dynamic Multileaf Collimation, IJORBP; 48, 1447-56, 2000.
• W. L. Straube; E. E. Klein; E. G. Moros; D. A. Low; R. J. Myerson. Dosimetry and techniques for simultaneous hyperthermia and external beam radiation therapy International Journal of Hyperthermia 17 (1): 48 – 62, 2000.
• Mutic, S., Low, D.A., Klein, E.E., Dempsey, J.F., Purdy, J.A. Room Shielding for Intensity Modulated Radiation Therapy Facilities, IJORBP, 50, 239-246, 2001.
• Low, D.A., Sohn, J. W., Klein, E.E., Markman, J., Mutic, S. Characterization of a Commercial Multileaf Collimator Used for Intensity Modulated Radiation Therapy, Med Phys, 28, 752-56, 2001.
• Boyer A, Klein, EE, et al. Basic applications of multileaf collimators: Report of Task Group No. 50. Radiation Therapy Committee, AAPM, Medical Physics, July, 2001.
• Klein, E.E., Low, D.A. Interleaf Leakage for 5 and 10 mm Dynamic Multileaf Collimation Systems Incorporating Patient Motion, Medical Physics, 28, 1703-10, 2001.
• Michalski JM, Klein EE, Gerber R, Method to plan, administer, and verify supine craniospinal irradiation J Appl Clin Med Phys 2002 Autumn;3(4):310-6.
• Kong FM, Klein EE, Bradley JD, Mansur DB, Taylor ME, Perez CA, Myerson RJ, Harms WB, The impact of central lung distance, maximal heart distance, and radiation technique on the volumetric dose of the lung and heart for intact breast radiation. Int J Radiat Oncol Biol Phys 2002 Nov 1;54(3):963-71.
• Klein EE, Esthappan J, Li Z, Surface and buildup dose characteristics for 6, 10, and 18 MV photons from an Elekta Precise linear accelerator. J Appl Clin Med Phys 2003 Winter;4(1).
• Jin JY, Klein EE., Kong FM, Li Z. A New Internal Mammary Irradiation Technique in Radiation Treatment of Locally Advanced Breast Cancers. J Appl Clin Med Phys , January, 2005.
• Klein EE, Balter JM, Chaney EL, Gerbi BJ, Hughes L. ASTRO’s Core Physics Curriculum for Radiation Oncology Residents. Int J Radiat Oncol Biol Phys. 2004 Nov 1;60(3):697-705.
• Papanikolaou N, Klein EE, et al. Tissue inhomogeneity corrections for megavoltage photon beams: Report of Task Group 65 of the Radiation Therapy Committee of the American Association of Physicists in Medicine. August, 2004, Medical Physics.
• Klein EE, Drzymala RE Purdy JA, Michalski, JM. Errors in Radiation Oncology: A Study in Pathways and Dosimetric Impact. J Appl Clin Med Phys, July, 2005.
• Klein EE., Maserang B, Wood R, Mansur DB, Peripheral Doses from Pediatric IMRT. Accepted for publication to Med. Phys, February, 2006.